• FC-G3501
  • 퓨쳐켐메브로페닌(Mebrofenin)
Cat. No. Packing Size Price($) Qty
FC-G3501-50 50 g on request
FC-G3501-100 100 g on request
FC-G3501-1000 1000 g on request
Information
Ligand for labeling with 99mTc
Synonyms N-(3-Bromo-2,4,6-trimethylacetanilido)imimodiacetic acid
CAS number 78266-06-5
M.F. C15H19BrN2O5
Mol. Wt. 387.23
Appearance White to off-white crystalline powder
Purity ≥97%
Certificate USP (Mebrofenin)
Reference

[Specification and Test method in the U.S.Pharmacopoeia]


TEST ITEM

ACCEPTANCE CRITERIA

DESCRIPTION

WHITE TO OFF-WHITE CRYSTALLINE POWDER

IDENTIFICATION

INFRARED ABSORPTION

MELTING RANGE

185 ~ 200

LOSS ON DRYING

NMT 0.3%

RESIDUE ON IGNITION

NMT 0.1%

LIMIT OF Nitrilotriacetic acid

NMT 0.1%

ORGANIC IMPURITIES

NMT 3.0%

ASSAY

97.0 ~ 101.0%


* Approval of drug manufacturing/marketing CODE : 202001873



[REFERENCE]


1. Nunn A. D. et al. A structure-distribution-relationship approach leading to the development of Tc-99m mebrofenin: an improved cholescintigraphic agent. J. Nucl. Med. 1983, 24, 423-430.

2. Krishnamurthy G. T. et al. Cholescintigraphic measurement of liver function: how is it different from other methods? Eur. J. Nucl. Med. Mol. Imaging 2006, 33, 1103-1106.

3. Bhargava K. K. et al. Adenosine triphosphate-binding cassette subfamily C member 2 is the major transporter of the hepatobiliary imaging agent 99mTc-mebrofenin. J. Nucl. Med. 2009, 50, 1140-1146.

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